The mainstream theory is that internal aging matches external aging.
Lifespan in short-lived organisms, such as D. melonogaster.
The body has an aging clock. Research should focus on slowing down this clock or, if possible, reversing it.
This is in contrast to most aging research, which is focused on clearing damage. In fact, although there are thousands of pathways in which damage accumulates in the human body, there are only about ten damage accumulations that are researched as causative of the exponential increase in human mortality. However, there has been little evidence that clearing any of the damage accumulations leads to an increase in maximal lifespan.
Suggested research programs
mimic the transcriptome of young bodies
blood borne factors